Methotrexate - Maxtrex - Ledertrexate Analysis
Laboratory analysis of drugs to certify the presence of methotrexate and measure the quantity of this active ingredient.
The level of uncertainty of the methotrexate content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).
Follow the instructions to send your drug to our laboratory for analysis.
Results within 15 working days of receipt of sample.
Methotrexate is a drug used to treat certain cancers, autoimmune diseases and chronic inflammatory disorders.
Methotrexate is the active ingredient in Maxtrex, marketed by Pfizer.
Consuming medicines ordered from dubious or illegal sites can be hazardous to your health. It is essential to check that the online pharmacy is serious and has all the necessary authorizations.
If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug complies with the indicated content.
Analysis
Methotrexate is analyzed by liquid chromatography coupled with detection by UV-Visible spectrophotometry (HPLC-UV Visible).
Chemical name
- Chemical name: (2S)-2-[[4-[[(2,4-diaminopteridin-6-yl)methyl]amino]benzoyl]amino]pentanedioic acid
- Gross formula: C20H22N8O5
- CAS number: 59-05-2
Therapeutic class
Methotrexate belongs to the class of antimetabolites (antineoplastics) and immunosuppressants.
Description of therapeutic effects
Methotrexate is used for :
- Oncological indications :
- Acute lymphoblastic leukemia
- Non-Hodgkin's lymphoma
- Choriocarcinoma
- Osteogenic sarcoma
- Breast or lung cancer (in certain cases)
- Non-oncological indications :
- Rheumatoid arthritis
- Severe psoriasis
- Juvenile idiopathic arthritis
- Severe inflammatory and autoimmune diseases
It acts by inhibiting the enzyme dihydrofolate reductase (DHFR), thus blocking the synthesis of DNA and RNA required for cell proliferation.
Trade names
- Methotrexate Teva (Teva Pharmaceuticals)
- Maxtrex (Pfizer)
- Ledertrexate (Sanofi)
- Generics available in several countries
Main manufacturers
- Teva Pharmaceuticals
- Pfizer
- Sanofi
- Hikma Pharmaceuticals
- Sandoz
Specific References
Your drug is analyzed by our expert pharmaceutical analysis laboratory.
The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.
The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.
The drug to be analyzed must be accompanied by the completed analysis form.
Documents to download:
The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:
- Absence of the active ingredient
- Under-dosage of the active ingredient
- Over-dosage of the active ingredient
- Toxic synthetic or degradation impurities
- Presence of another active ingredient
- Toxic excipients
- Presence of toxic residual solvents
- ...
The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.