Vardenafil - Levitra - Staxyn - Vivanza Analysis

Vardenafil is a popular drug used to treat erectile dysfunction.

Vardenafil is the active ingredient in Levitra, marketed by the Bayer laboratory.

Because of its popularity, Vardenafil is one of the most widely sold drugs on the Internet, and also one of the most counterfeited on the market.

Consuming drugs ordered from dubious or illegal sites poses a health risk. It is essential to check that the online pharmacy is serious and has all the necessary authorizations.

If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug complies with the indicated content.

Chemical name

• Chemical name: 2-(2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4-one
• Chemical formula: C23H32N6O4S
• CAS number: 224785-91-5

Therapeutic class

• Therapeutic class: Phosphodiesterase type 5 (PDE-5) inhibitor
• Main indications: Erectile dysfunction

Description of Therapeutic Effects

Vardenafil is a drug used to treat erectile dysfunction (impotence) in men. It works by increasing blood flow to the penis, enabling an erection in response to sexual stimulation.

• Mechanism of action:
  
  • Vardenafil inhibits the enzyme phosphodiesterase type 5 (PDE-5), responsible for the degradation of cyclic GMP (cGMP).
  • By inhibiting PDE-5, it increases levels of cGMP, thereby promoting smooth muscle relaxation and blood vessel dilation in the penis, facilitating an erection.
• Duration of action:
  
  • The effect of vardenafil generally begins within 30 minutes of administration and lasts approximately 4 to 6 hours.

Trade names

Vardenafil is marketed under several names:

• Levitra: The best-known brand name, manufactured by Bayer.
• Staxyn: An orodispersible version (tablet that melts in the mouth) for rapid use.
• Vivanza: Used in some countries for specific formulations.
• Generic Vardenafil: Available in generic form in many countries, often at reduced cost.

Main Manufacturers

Leading manufacturers of vardenafil include:

• Bayer AG: The original developer of Levitra, which remains one of the leading producers.
• GlaxoSmithKline (GSK): Collaborated with Bayer for initial commercialization.
• Merck & Co: Participated in distribution in certain markets.
• Teva Pharmaceuticals: Supplies generic versions.
• Cipla: Major player in the production of generic versions, particularly in India.
• Sun Pharmaceutical Industries: Supplier of generic vardenafil to international markets.
• Dr. Reddy's Laboratories: Producer of cost-effective generic formulations.

Precautions and side effects

Precautions :

• Contraindicated in patients taking nitrates (risk of dangerous drop in blood pressure).
• Use with caution in patients with heart disease, hypertension, or severe liver or kidney disease.
• Avoid excessive alcohol consumption, which may reduce the effectiveness of the drug.
• Do not take more than one dose a day.

Common side effects:

• Headache.
• Facial flushing.
• Nasal congestion.
• Digestive disorders (dyspepsia).
• Dizziness.

Serious side effects (rare):

• Priapism (prolonged, painful erection requiring urgent medical attention).
• Sudden loss of vision or hearing.
• Severe allergic reactions (angioedema, rash).