Chemical formula of Melatonin
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Melatonin - Circadin Analysis

€99.00
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MELATONINE

Laboratory analysis of drugs and dietary supplements to certify the presence of melatonin and measure its concentration.

The level of uncertainty of the melatonin content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).

Follow the instructions to send your medication or dietary supplement to our laboratory for analysis.

Results within 15 working days of receipt of sample.

Analysis: Standard

Melatonin is a natural hormone involved in regulating the sleep-wake cycle. It is used as a supplement or medication to treat sleep disorders, notably insomnia and jet lag.

Melatonin is the active ingredient in Circadin, marketed by Neurim Pharmaceuticals, as well as in several other formulations available as dietary supplements or medicines.

Consuming medicines or dietary supplements ordered from dubious or illegal sites can present a health risk. It is essential to check that the online pharmacy is reputable and fully licensed.

If you have any doubts about the origin of the drug or dietary supplement, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug or dietary supplement complies with the stated content.

Analysis

Melatonin is analyzed by liquid chromatography coupled with detection by UV-Visible spectrophotometry (HPLC-UV Visible).

Chemical name

  • Chemical name: N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide
  • Gross formula: C13H16N2O2
  • CAS number: 73-31-4

Therapeutic class

Melatonin belongs to the class of hormones and regulators of the sleep-wake cycle, used mainly for :

  • Treatment of insomnia (especially in the elderly).
  • Managing jet lag in frequent travellers.
  • Improving sleep in the case of night shifts or circadian rhythm disorders.
  • Experimental use in neurology and oncology for its antioxidant and neuroprotective effects.

Description of therapeutic effects

Melatonin is a hormone produced naturally by the pineal gland, which regulates the sleep-wake cycle according to the alternation of day and night.

  • Helps induce sleep faster and improve its quality.
  • More pronounced in the elderly, whose melatonin production declines with age.
  • Helps resynchronize the biological clock after jet lag or night shifts.
  • Antioxidant role that could have protective effects against certain neurodegenerative diseases.

Trade names

  • Circadin (sustained-release drug)
  • Melatonine Biogaran
  • Melatonine Sandoz
  • Melatonin-based dietary supplements under various brand names

Principaux fabricants

  • Neurim Pharmaceuticals
  • Biogaran
  • Sandoz
  • Arkopharma (dietary supplements)
  • Nature’s Plus (dietary supplements)

Precautions and side effects

Precautions for use

  • Not recommended for people with severe psychiatric disorders.
  • Do not combine with alcohol, which alters its efficacy.
  • May interact with drugs (antidepressants, anticoagulants, immunosuppressants).
  • Use with caution in people suffering from epilepsy or autoimmune diseases.
  • Avoid during pregnancy and breast-feeding, except on medical advice.

Possible side effects

  • Common: daytime drowsiness, headaches, dizziness, nausea.
  • Occasional: irritability, nightmares, dry mouth.
  • Rare but serious: allergic reactions, hormonal disorders if taken for long periods at high doses.

⚠️ Drug interactions: Melatonin may potentiate the effect of sleeping pills, benzodiazepines and anticoagulants.

MELATONINE

Specific References

Your drug is analyzed by our expert pharmaceutical analysis laboratory.

The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.

The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.

The drug to be analyzed must be accompanied by the completed analysis form.

Documents to download:

The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:

  • Absence of the active ingredient
  • Under-dosage of the active ingredient
  • Over-dosage of the active ingredient
  • Toxic synthetic or degradation impurities
  • Presence of another active ingredient
  • Toxic excipients
  • Presence of toxic residual solvents
  • ...

The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.

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Melatonin - Circadin Analysis

€99.00