Metformin - Glucophage - Stagid - Metformax - Diabex - Siofor Analysis
Laboratory analysis of drugs to certify the presence of metformin and measure its concentration.
The level of uncertainty of the metformin content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).
Follow the instructions to send your drug to our laboratory for analysis.
Results within 15 working days of receipt of sample.
Metformin is an oral anti-diabetic medication used primarily in the treatment of type 2 diabetes. It helps control blood sugar levels by reducing hepatic glucose production and improving cell sensitivity to insulin.
Consuming medicines ordered from dubious or illegal sites presents a health risk. It is essential to check that the online pharmacy is reputable and fully licensed.
If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage is in line with the indicated content.
Analysis
Metformin is analyzed by liquid chromatography coupled with UV-Visible spectrophotometric detection (HPLC-UV Visible).
Chemical name
- Chemical name: 1,1-dimethylbiguanide
- Gross formula: C4H11N5
- CAS number: 657-24-9
Therapeutic class
Metformin belongs to the biguanide class, used as first-line treatment for type 2 diabetes. It is also being studied for other indications, such as polycystic ovary syndrome (PCOS) and diabetes prevention in high-risk individuals.
Description of therapeutic effects
Metformin acts mainly by :
- Reduces hepatic glucose production (inhibition of gluconeogenesis).
- Improves cell sensitivity to insulin, promoting blood glucose absorption.
- Reduces intestinal glucose absorption.
Its main advantages are :
- Effective in glycemic control without causing hypoglycemia.
- Beneficial effect on weight, often neutral or slightly favoring weight loss.
- Demonstrated cardiovascular protection in diabetic patients.
Trade names
- Glucophage
- Stagid
- Metformax
- Diabex
- Siofor
Main manufacturers
- Merck
- Teva Pharmaceuticals
- Mylan
- Sandoz
- Sanofi
Precautions and side effects
Precautions for use
- Do not use in cases of severe renal failure (risk of lactic acidosis).
- Avoid excessive alcohol consumption, which increases the risk of lactic acidosis.
- To be temporarily discontinued before an examination involving injection of iodinated contrast media, to avoid renal toxicity.
- Not recommended for people with severe hepatic impairment.
- Caution in case of dehydration or severe infection.
Possible side effects
- Frequent digestive disorders: nausea, diarrhea, abdominal pain (generally transient).
- Metallic taste in the mouth.
- Rare but serious risk: lactic acidosis, especially in cases of renal failure.
- Long-term vitamin B12 deficiency, requiring regular monitoring.
⚠️ Drug interactions :
- Non-steroidal anti-inflammatory drugs (NSAIDs) increase the risk of lactic acidosis.
- Corticosteroids and certain diuretics can reduce its effectiveness.
- Potentiation with other antidiabetic agents requires dose adjustment.
Specific References
Your drug is analyzed by our expert pharmaceutical analysis laboratory.
The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.
The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.
The drug to be analyzed must be accompanied by the completed analysis form.
Documents to download:
The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:
- Absence of the active ingredient
- Under-dosage of the active ingredient
- Over-dosage of the active ingredient
- Toxic synthetic or degradation impurities
- Presence of another active ingredient
- Toxic excipients
- Presence of toxic residual solvents
- ...
The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.