Miconazole - Daktarin - Monistat - Gyno-Daktarin Analysis
Laboratory analysis of drugs to certify the presence of miconazole and measure its concentration.
The level of uncertainty of the miconazole content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).
Follow the instructions to send your drug to our laboratory for analysis.
Results within 15 working days of receipt of sample.
Miconazole is an imidazole antifungal agent used primarily for the treatment of cutaneous, vaginal and oral fungal infections, including candidiasis and dermatophytosis.
Miconazole is the active ingredient in Daktarin, marketed by Janssen Pharmaceuticals, as well as several other generics.
Consuming medicines ordered from dubious or illegal sites can be hazardous to your health. It is essential to check that the online pharmacy is reputable and fully licensed.
If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug complies with the indicated content.
Analysis
Miconazole is analyzed by liquid chromatography coupled with UV-Visible spectrophotometric detection (HPLC-UV Visible).
Chemical name
- Chemical name: 1-[2-(2,4-Dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazole
- Gross formula: C18H14Cl4N2O
- CAS number: 22916-47-8
Therapeutic class
Miconazole belongs to the class of imidazole antifungals, used mainly for :
- Treatment of fungal infections of the skin (cutaneous mycoses, dermatophytoses).
- Treatment of oral and vaginal candidiasis.
- Treatment of systemic fungal infections (rarer, in intravenous formulation).
Description of therapeutic effects
Miconazole acts by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, leading to their destruction.
- Effective against Candida, Aspergillus and dermatophytes.
- Used in the form of cream, oral gel, powder or ova for topical application.
- In intravenous formulation, it is indicated for certain serious systemic fungal infections.
Trade names
- Daktarin
- Monistat
- Gyno-Daktarin
- Miconazole Viatris
- Other generics available
Main manufacturers
- Janssen Pharmaceuticals
- Viatris
- Teva Pharmaceuticals
- Sandoz
- Pfizer
Precautions and side effects
Precautions for use
- Contraindicated in cases of hypersensitivity to azole antifungals.
- Mainly for topical use, but the oral or IV form should be used with caution in cases of hepatic insufficiency.
- Possible drug interactions with anticoagulants (warfarin), certain antidiabetics and other drugs metabolized by CYP3A4.
- Not recommended during pregnancy or breast-feeding without medical advice.
Possible side effects
- Common: itching, local irritation, burning sensation.
- Occasional: gastrointestinal disorders when administered orally (nausea, diarrhea).
- Rare but serious: allergic reactions, hepatotoxicity, drug interactions increasing risk of bleeding on anticoagulants.
⚠️ Drug interactions: Miconazole increases the effect of oral anticoagulants, requiring close monitoring of coagulation levels.
Specific References
Your drug is analyzed by our expert pharmaceutical analysis laboratory.
The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.
The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.
The drug to be analyzed must be accompanied by the completed analysis form.
Documents to download:
The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:
- Absence of the active ingredient
- Under-dosage of the active ingredient
- Over-dosage of the active ingredient
- Toxic synthetic or degradation impurities
- Presence of another active ingredient
- Toxic excipients
- Presence of toxic residual solvents
- ...
The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.