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Cloxacillin - Orbenin - Tegopen Analysis
€149.00
Tax included
CLOXACILLINE
Laboratory analysis of drugs to certify the presence of cloxacillin and measure its concentration.
The level of uncertainty of the cloxacillin content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).
Follow the instructions to send your drug to our laboratory for analysis.
Results within 15 working days of receipt of sample.
Cloxacillin is a beta-lactamase-resistant penicillin antibiotic used to treat bacterial infections caused by sensitive staphylococci.
Consuming medicines ordered from dubious or illegal sites presents a health risk. It is essential to check that the online pharmacy is reputable and fully licensed.
If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage is in line with the indicated content.
Analysis
Cloxacillin is analyzed by liquid chromatography coupled with detection by UV-Visible spectrophotometry (HPLC-UV Visible).
Chemical name
- Chemical name: (2S,5R,6R)-6-[[(3-chlorophenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- Gross formula: C19H18ClN3O5S
- CAS number: 61-72-3
Therapeutic class
Cloxacillin belongs to the beta-lactam antibiotic class, a subgroup of beta-lactamase-resistant penicillins, effective against :
- Skin and soft-tissue infections (impetigo, abscesses, boils).
- Osteoarticular infections (osteomyelitis, septic arthritis).
- Pulmonary infections (staphylococcal pneumonia).
- Sensitive staphylococcal endocarditis.
Description of therapeutic effects
Cloxacillin is a penicillin resistant to beta-lactamases produced by staphylococci, making it effective against these bacteria, which are resistant to conventional penicillins.
- Bactericidal action, inhibiting bacterial wall synthesis.
- Mainly effective against methicillin-sensitive staphylococci (MSSC).
- Less active against streptococci and ineffective against Gram-negative bacteria.
Trade names
- Orbenin
- Cloxacilline Mylan
- Cloxacilline Sandoz
- Tegopen
Main manufacturers
- GlaxoSmithKline
- Mylan
- Sandoz
- Sanofi
- Teva Pharmaceuticals
Precautions and side effects
Precautions for use
- For best absorption, administer on an empty stomach (1 hour before or 2 hours after a meal).
- Monitor in case of renal or hepatic insufficiency.
- Do not use if allergic to penicillins or beta-lactams in general.
- Use with caution in patients with mononucleosis, as beta-lactam antibiotics may cause skin rashes.
Possible side effects
- Common: digestive disorders (nausea, diarrhea), abdominal pain.
- Occasional: allergic skin reactions (rash, pruritus).
- Rare but serious: anaphylactic shock, hepatotoxicity, pseudomembranous colitis (due to Clostridium difficile).
⚠️ Drug interactions :
- Decreased efficacy of oral contraceptives.
- Increased risk of adverse effects in association with methotrexate (increased toxicity).
- Interaction with probenecid, increasing cloxacillin plasma concentration.
CLOXACILLINE
Specific References
Your drug is analyzed by our expert pharmaceutical analysis laboratory.
The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.
The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.
The drug to be analyzed must be accompanied by the completed analysis form.
Documents to download:
The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:
- Absence of the active ingredient
- Under-dosage of the active ingredient
- Over-dosage of the active ingredient
- Toxic synthetic or degradation impurities
- Presence of another active ingredient
- Toxic excipients
- Presence of toxic residual solvents
- ...
The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.
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