Chemical formula of Hydrocortisone
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Hydrocortisone - Cortef - Hydrocortone - Solu-Cortef - Cortisol Analysis

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HYDROCORTISONE

Laboratory analysis of medication to certify the presence of hydrocortisone and measure its concentration.

The level of uncertainty of the hydrocortisone content analysis depends on the declination selected (Standard <20%, Precise <10% or Regulatory <5%).

Follow the instructions to send your drug to our laboratory for analysis.

Results within 15 working days of receipt of sample.

Analysis: Standard

Hydrocortisone is a glucocorticoid, mainly used in the treatment of inflammation, allergies, adrenal insufficiency and autoimmune diseases. Hydrocortisone is included in the World Health Organization (WHO) list of essential medicines.

Hydrocortisone is the active ingredient in several drugs, including Cortef and Hydrocortone, marketed by several pharmaceutical companies.

Consuming medicines ordered from dubious or illegal sites can be hazardous to your health. It is essential to check that the online pharmacy is reputable and fully licensed.

If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug complies with the indicated content.

Analysis

Hydrocortisone is analyzed by liquid chromatography coupled with detection by UV-Visible spectrophotometry (HPLC-UV Visible).

Chemical name

  • Chemical name: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
  • Gross formula: C21H30O5
  • CAS number: 50-23-7

Therapeutic class

Hydrocortisone belongs to the glucocorticoid class, used mainly for :

  • Treatment of inflammation and severe allergic reactions
  • Treatment of adrenal insufficiency (e.g. Addison's disease)
  • Relief of symptoms of autoimmune diseases
  • Treatment of inflammatory skin conditions (eczema, psoriasis, dermatitis)

Description of therapeutic effects

Hydrocortisone is a corticosteroid hormone that regulates inflammation and the metabolism of carbohydrates, lipids and proteins.

  • Anti-inflammatory effect: reduces swelling, redness and pain.
  • Immunosuppressive effect: reduces immune system response in autoimmune diseases.
  • Hormonal effect: replaces cortisol in cases of adrenal insufficiency.

Trade names

  • Cortef
  • Hydrocortone
  • Solu-Cortef
  • Cortisol
  • Numerous dermatological creams (e.g. Hydrocortisone 1%)

Main manufacturers

  • Pfizer
  • Sanofi
  • Novartis
  • Teva Pharmaceuticals
  • Mylan

Precautions and side effects

Precautions for use

  • Avoid in cases of uncontrolled infection, as hydrocortisone can weaken the immune system.
  • Prolonged use may cause adrenal insufficiency due to cessation of natural cortisol production.
  • Risk of hypertension, hyperglycemia and osteoporosis with prolonged use.
  • For hydrocortisone-based creams: do not apply to open wounds or untreated skin infections.

Possible side effects

  • Common: weight gain, facial swelling, insomnia, restlessness.
  • Occasional: hypertension, muscle weakness, digestive disorders.
  • Rare but serious: adrenal insufficiency, osteoporosis, cataracts.

⚠️ Possible interactions: Certain drugs (antidiabetics, anticoagulants, anti-inflammatories) can modify the effect of hydrocortisone.

HYDROCORTISONE

Specific References

Your drug is analyzed by our expert pharmaceutical analysis laboratory.

The drug to be analyzed must be sent in at least 3 copies in its original packaging (box or vial + blister pack) in order to have all the information.

The drug to be analyzed must be sufficiently protected to avoid any deterioration or damage during transport.

The drug to be analyzed must be accompanied by the completed analysis form.

Documents to download:

The use of counterfeit or illegal medicines (without patent authorisation) presents a proven risk to patients' health:

  • Absence of the active ingredient
  • Under-dosage of the active ingredient
  • Over-dosage of the active ingredient
  • Toxic synthetic or degradation impurities
  • Presence of another active ingredient
  • Toxic excipients
  • Presence of toxic residual solvents
  • ...

The trade in counterfeit medicines is flourishing and growing exponentially with online trading. The authorities believe that more than half of all medicines sold over the Internet are counterfeit or illegal.

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Hydrocortisone - Cortef -...

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