Ketoprofen - Profenid - Ketum - Actron Analysis

Ketoprofen is a drug used to treat fevers, mild to moderate pain and inflammation.

Ketoprofen is the active ingredient in Profenid, marketed by the Sanofi laboratory.

Ordering medicines from dubious websites can be risky for your health. It is essential to check that the online pharmacy is serious and has all the necessary authorizations.

If you have any doubts about the origin of the drug, you should carry out an analysis to certify the presence of the active ingredient and check that its dosage in the drug complies with the indicated content.

Analysis

Ibuprofen is analyzed by liquid chromatography coupled with UV-Visible spectrophotometric detection (HPLC-UV Visible).

Chemical name

• Chemical name: (RS)-2-(3-benzoylphenyl)propanoic acid
• Chemical formula: C16H14O3
• CAS number: 22071-15-4

Therapeutic class

• Therapeutic class: Non-steroidal anti-inflammatory drugs (NSAIDs)
• Subclass: Analgesics, antipyretics and anti-inflammatories

Description of Therapeutic Effects

Ketoprofen is an NSAID used for its anti-inflammatory, analgesic and antipyretic effects. It acts primarily by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins responsible for pain, inflammation and fever.

• Therapeutic indications :
  
  • Acute and chronic pain: musculoskeletal pain, post-operative pain, sprains, low back pain.
  • Inflammations: Rheumatoid arthritis, ankylosing spondylitis, osteoarthritis.
  • Dysmenorrhea: Relief of menstrual pain.
  • Fever: In certain cases, to lower high body temperature.
  • Local ailments: Used as topical gels to treat localized pain and inflammation (sprains, tendonitis).
• Main effects :
  
  • Reduced pain and inflammation.
  • Improves mobility in rheumatic conditions.

Trade names

Ketoprofen is marketed under various names worldwide:

• Profenid: Well-known brand used for oral, injectable and topical formulations.
• Ketum: Mainly available as a topical gel.
• Oki: Used in some countries for oral and powder formulations.
• Actron: Brand distributed in certain markets.
• Fastum: Gel formulation widely used for the treatment of local pain.
• Flamax: Names available in injectable and oral versions.

Main Manufacturers

Several manufacturers produce ketoprofen under brand names or in generic form:

• Sanofi: Producer of Profenid, a leading brand of ketoprofen.
• Menarini: Manufacturer of Ketum and Fastum, popular topical gels.
• Aurobindo Pharma: Supplier of generic formulations in various markets.
• Sun Pharmaceutical Industries: Manufacturer of generics, notably in Asia.
• Mylan (Viatris): Supplier of generic versions worldwide.
• Teva Pharmaceuticals: Distribution of generic versions in Europe and North America.
• Dr. Reddy's Laboratories: Major player in generics production, notably in India and Africa.
• Novartis (Sandoz): Distributor of generic tablet and gel formulations.

Precautions and side effects

• Precautions :
  • Contraindicated in people with a history of gastric ulcers, cardiac, renal or hepatic insufficiency.
  • Avoid prolonged exposure to sunlight when using topical gels, as photosensitivity may occur.
  • Do not use during the third trimester of pregnancy.
• Common side effects:
  
  • Gastrointestinal disorders: nausea, abdominal pain, diarrhea, dyspepsia.
  • Skin reactions (mainly with topical gels): Redness, pruritus, photosensitivity.
• Serious side effects:
  
  • Gastric ulcers or digestive bleeding.
  • Kidney or liver failure.
  • Severe allergic reactions, including angioedema.
  • Increased cardiovascular risk with prolonged or high-dose use.